Journal of Thermal Science and Technology
Online ISSN : 1880-5566
ISSN-L : 1880-5566
Papers
Nonthermal Plasma-Mediated Cancer Cell Death; Targeted Cancer Treatment
Byul-Bora CHOI, Yeon-Sik CHOI, Hae-Jun LEE, Jae-Koo LEE, Uk-Kyu KIM, Gyoo-Cheon KIM
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Keywords: Cancer Cell Death, Non-Thermal Plasma, Gold Nanoparticle, Antibody
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2012 Volume 7 Issue 2 Pages 399-404

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Abstract
Non-thermal air plasma can kill cancer cells. However, there is no selectivity between normal and cancer cells. Therefore, cancer specific antibody conjugated gold nanoparticle (GNP) was pretreated before plasma irradiation. Stimulation of antibody conjugated GNP by plasma treatment resulted in a significant decrease in viability of cancer cells. This technology shows the feasibility of using plasma therapy for killing cancer cells selectively.
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© 2012 by The Japan Society of Mechanical Engineers and The Heat Transfer Society of Japan
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