Concurrently Arisen Adenocarcinoma and Leiomyoma of the Uterus in a Rabbit

Abstract

A 6-year and 11-month old rabbit manifested severe bleeding from the vulva. Since a uterine neoplasm was suspected based on the radiographic examination, an ovariohysterectomy was performed. A large mass, approximately 35 × 50 mm, was observed in the right uterine horn and bead-shaped nodular lesions, 10–20 mm in size, were found in the left uterine horn. Histopathological and immunohistochemical examinations revealed papillary adenocarcinoma in the right uterine horn and leiomyoma in the left uterine horn. The rabbit could survive for 3 years and 9 months after the surgery without any specific symptoms, and it died at the age of 10 years and 8 months showing thoracic disorder.