Abstract
Minute electric current caused in the inflammatory changes at the trauma between the two electrodes, as well as at the site of both electrodes. The inflammation was intensified irrespective of the polarity of the electrodes, and in three days the signs of acute inflammation was apparent, including marked edema, hyperemia and infiltration with neutrophilic granulocytes, histiocytes and monocytes. The blood vessels around the lesion were found to be distended. After the end of electrical stimulation, the extent of inflammation was reduced to the level before the electric stimulation. This inflammation, mainly characterized by hyperemia and edema, was considerd as follows. When electricity was applied, the current which flowed in the blood stream and extracellular fluid intensified the inflammatory changes by transferred ions. Thus, the local temperature rose by granulocytic pyrogens and hyperemia, and histamine like substance and serotonin were released. Then the vascular permeability was increased and induced the maintenance of the increase in acute inflammatory cellular infiltration.
