Abstract
With radiotherapy, local recurrence of nasal tumors remains challenging. Re-irradiation was performed intermittently to control clinical signs until central nervous system(CNS)signs occurred in a 9-year-old spayed Yorkshire terrier that had completed radiotherapy to the nasal cavity 452 days earlier for intranasal adenocarcinoma(44 Gy/11 fractions/1 month). For radiotherapy, a linear accelerator was used with no margin to preserve normal tissues at a radiation dose at the isocenter of 5-8 Gy. Because the tumor responded well, re-irradiation was planned for recurrent clinical signs. On day 1,600, the dog died, allegedly due to tumor progression and CNS invasion or because of brain necrosis as a radiation side effect. Improved survival is considered achievable with re-irradiation.
