2016 Volume 69 Issue 1 Pages 41-45
An 11-year-old intact, male Maltese dog was referred to the Osaka Prefecture University Veterinary Teaching Hospital due to a large cyst in the abdominal cavity and left adrenomegaly. A physical examination revealed marked abdominal distention and respiratory effort on day 1. An abdominal ultrasound revealed the soft tissue structure to be a cyst-like mass, which appeared to be connected to the enlarged left adrenal gland. On day 7, a computed tomography (CT) scan was performed to plan the surgical removal of the left adrenal gland and cyst-like mass. The CT scan revealed a large cyst in the left mid-abdominal cavity extruding from the enlarged left adrenal gland (2.0×2.5 cm) and atrophy of the right adrenal gland (0.2×0.3 cm). Based on histopathological and immunohistochemical findings, the cyst was diagnosed as a neuroblastoma arising in the adrenal medulla, and the enlarged left adrenal gland was diagnosed as an adrenocortical adenocarcinoma. Neuroblastoma arising in the adrenal medulla of dogs has rarely been reported, and this case was considered extremely rare with a concurrent diagnosis of adrenocortical adenocarcinoma.