Abstract
We have investigated nerve cell-attachment properties of Poly-Lactic-Acid (PLA) surface modified by carbon negative-ion implantation. PLA is one of the absorbable polymers used in medical surgery. PLA sheets were implanted with carbon negative-ions at an energy in a range of 5-30 keV with dose in 1 × 1014-1 × 1016 ions/cm2. Contact angle for the PLA implanted at 5 keV showed a large value of 94° at a dose of 1 × 1014 ions/cm2, and then it decreased with an increase in dose to 80°. For the samples at 3 × 1015 ions/cm2, the contact angle slightly decreased from 82° to 78° as increasing in ion energy. In the nerve cell culture experiment with nerve cells of PC 12h cell (rat adrenal pheochromocytoma), selective cell attachment properties were obtained. The nerve cells attached on the unimplanted area in Carbon-implanted PLA samples at 5 and 10 keV, on the other hand, they attached on only implanted area for 30 keV C-implanted PLA sample.
