Abstract
The influence of a nucleic acid-related substance on Pleurotus nebrodensis cultivation was assessed in terms of mycelial growth and pharmacological effects. The addition of the nucleic acid-related substance facilitated the growth of mycelia in all culture media, i.e., liquid, agar and sawdust. The growth-facilitating effect of the nucleic acid-related substance was highest at 0.1% concentration in liquid and agar media. The results of tests for anti-platelet aggregation and chemokine gene expression inhibition demonstrated that mycelia tended to be active when cultured with addition of the nucleic acid-related substance to the medium. Pharmacological effects were absolutely attributed to the additive.
