Development of Simultaneous Analytical Method for Nine Haloacetic Acids(HAAs) in Drinking Water by Liquid Chromatography - Electrospray Tandem Mass Spectrometry (LC/MS/MS) and Effect of Condition in Preserving HAAs Standard Solutions

Abstract

We have developed a simultaneous analytical method for nine haloacetic acids (HAAs) in drinking water included a highly-concentrated matrix by liquid chromatography-electrospray tandem mass spectrometry (LC/MS/MS).Under the optimized method conditions, the recovery rates of the compounds from highly-concentrated matrix (Cl－:177mg/L, Na+,Ca2+,SO42－, CO32－:100mg/L, NO3－:100mgN/L) were within the range of 71-118%, with relative standard deviations of 1.6-14.5%, respectively. The concentration of HAAs within tert-buthyl methyl ether are not changed as long as 560 days. Several days later, the concentration of HAAs within methanol or ethanol are gradually reduced even as for the freezing preservation. The decrease was remarkable by increasing the heat and assuming it mixed standard solution. Therefore, attention is required in preserving HAAs standard solutions.