Preliminary Study on Unreliability of Lymphocyte Stimulating Test for Kampo Medicine

Naoki MANTANI; Harumi MATSUDA; Eiichi TAHARA; Shinya SAKAI; Toshiaki KOGURE; Hirozo GOTO; Naotoshi SHIBAHARA; Toshiaki KITA; Takahiro SHINTANI; Yutaka SHIMADA; Takashi ITO; Katsutoshi TERASAWA

doi:10.3937/kampomed.51.1093

Naoki MANTANI, Harumi MATSUDA, Eiichi TAHARA, Shinya SAKAI, Toshiaki KOGURE, Hirozo GOTO, Naotoshi SHIBAHARA, Toshiaki KITA, Takahiro SHINTANI, Yutaka SHIMADA, Takashi ITO, Katsutoshi TERASAWA

Author information

Naoki MANTANI
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Harumi MATSUDA
Matsuda clinic
Eiichi TAHARA
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Shinya SAKAI
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Toshiaki KOGURE
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Hirozo GOTO
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Naotoshi SHIBAHARA
Department of Kampo Diagnostics, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
Toshiaki KITA
Department of Kampo Diagnostics, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
Takahiro SHINTANI
Department of Japanese Oriental Medicine, Kanebo Memorial Hospital
Yutaka SHIMADA
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Takashi ITO
Department of Kampo Diagnostics, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
Katsutoshi TERASAWA
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University

Keywords: lymphocyte stimulating test, false-positive, Kampo medicine, side effect

JOURNAL FREE ACCESS

2001 Volume 51 Issue 5 Pages 1093-1099

DOI https://doi.org/10.3937/kampomed.51.1093

Details

Abstract

We performed a preliminary study of the reliability of the lymphocyte stimulating test (LST) for Kampo medicine. LST for three kinds of Kampo medicines was performed in both a Kampo-administrated group and a non-administrated group. LST for each of the medicines was negative for seven of eight subjects in the non-administrated group, but was negative for four of 11 subjects in the Kampo-administrated group. The LST-positive participants had no allergic state, and some among them were negative in challenge test. This preliminary study suggests that LST for Kampo medicine is likely to be false-positive.

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