Acute Colitis due to Salmonella changhai

Abstract

Two cases of acute colitis due to salmonella changhai were experienced in Matsuyama, Ujiie, Tochigi Prefecture. The major symptoms consisted of high fever (40°C at maximum), vomiting (twice a day), headache and abdominal pain with muddy stools containing mucus. One of the patients showed Ekiri-like symptoms. Both cases were well controlled by the administation of streptomycin and thiazin, for a week.
A gram-negative rod isolated from both patients demonstrated general characteristics of salmonella, and on the other hand, the convalescent sera showed a high agglutinin titer against it. The organism with an antigenic structure 16: 1, v: 1, 6 proved to be serologically entirely identical with salmonella changhai by the cross-agglutinin-absorbtion tests.
From the above findings, it was concluded that the acute colitis was caused by salmonella changhai.