Studies on the Streptococcus Hemolyticus Infection

Abstract

Bacteriological and serological studies were carried out an 27 cases of acute glomerulonephritis and 12 cases of scarlet fever from November 1956 to November 1957 in our department of pediatrics.
The results were as follows;
1) The antistreptolysin titer was slightly or markedly elevated in 25 casee of acute glomerulonephritis except for one case with a normal value showing nephrotic symptoms. All cases of scarlet fever demonstrated the highest titer after two weeks from the onset.
2) All the 12 strains of streptococcus hemolyticus isolated from glomerulonephritis were classified into group A after Lancefield, one belonging to type 12. Also 8 strains isolated from scarlet fever were classified into group A.
3) The strains isolated showed the highest sensitivity to penicillin, which decreased in the order of erythromycin, tetracyclin and chloramphenicol. Resistance was found highest against streptomycin.
4) Tonsillectomy was performed on 7 cases of glomerulonephritis with chronic tonsillitis, whereafter antistreptolysin titer usuatlly came down.