Type and Drug-Resistance of Shigella Bacilli isolated in Nagoya City in 1965

with Special Reference to the Isolation of Shigella Boydii 5

Abstract

The number of patients admitted to this hospital from various part of Nagoya city under the diagnosis of bacillary dysentery or its suspect or the carrier during a year 1965 was 544 in total. Those from whom eShigella were isolated were 321 (59.0%).
Through the year, February had largest number of incidence (45) and October, the least (15). The isolation rate was highest in November (82.9%), lowest in July (41.3%).
In type distribution, Sh. sonnei was predominant (181, 56.4%), followed by Sh. flexnery 3a (58, 18.1%). Other types were each. less than 10.0%
Out of isolated 321 strains, 201 (62.6%) were proved to be treble-, duple- or single-drug-resistant against such antibiotics as streptomycin (SM), chloramphenicol (CM) and tetracycline (TC). Of them, the vast majority (283, 91.0%) were treble (SM CM TC)-drug-resistant strains, others being each. less than 5.0% None of strains resistant to CM alone was encountered. Against sulfonamide (SA), 267 (83.2%) were resistant. Above mentioned treble-drug-resistant strains were all proved resistant to SA at the same time. Against kanamycin, none of 207 strains tested was resistant.
Massive outbreaks, involving more than 10 patients in one occasion, were only two (11 and 31 patients respectively). The germ isolation rate was 100% in the former, 87.1 % in the latter. The germs were all. Sh. sonnei and multiple (SM CM TC SA)-drug- resistant.
Two strains of Sh. boydii 5 were obtained in this survey, for the first time as far as Nagoya city is, concerned. One was isolated from a patient in this hospital, and another, from the material sent from theother institution. The both were sensitive either to antibiotics or to SA.
Vibrio enteritidis isolated through the year were only four. The number was remarkably lowerthan ever. All were belonging to type 1 in biological properties.