1967 Volume 41 Issue 2 Pages 69-81
Clinical observations were made on Japanese Encephalitis in aged person with the following results
Outbreaks of Japanese Encephalitis in Kyoto province have been seen in every summer, and the epidemic in 1966 was the largest among them.
2) The recent trend in age distribution has been that more than 60 per cent of the patients were over 41 years of age.
3) The clinical pictures of old age were severe in general and death rate increased as the age advanced.
4) The fatality rate in male of old age groups was higher than in female.
5) The initial pressure of cerebrospinal fluid and the degree of pleocytosis of it were lower in older. age groups than in younger age groups.
6) Many healthy people of the older generation possessed HI antibodies.
7) In recovered cases, the HI antibody titer, after reaching a maximum level, declined more rapidly in older age groups than in younger age groups.
8) The HI antibody titers in the early stage of older age groups were much lower in dead cases than in recovered cases.
9) The CF antibody titers of recovered cases declined with advancing age.
10) Follow-up study revealed that many recovered cases of older age suffered from several sequelae.
11) The urinary 17-OHCS levels of older cases treated with ACTH or ACTH combined with gucocorticoid were markedly higher in recovered cases than in death cases in whom no noticeable response to ACTH was seen.
