Protective Effect of Glycolipid Containing Mycolic Acid Derived from Gordona aurantiaca Against Yersinia enterocolitica

Abstract

Trehalose trimycolate derived from Gordona aurantiaca (Ga-GM) was examined on protection effect against Yersinia enterocolitica infection of mouse. Intravenous administration of Ga-GM with w/o/w emulsion 6 days before infection protected BALB/c mice against infection with Y. enterocolitica mouse than a LD₅₀. The protection of BALB/c mouse was observed only when Ga-GM was administered 6 days before infection, but not when administered 2 days before or simultaneously.