Study of the Pathogenecity of Enterococcus faecalis-Experimental Mice Mixed Infection with E. faecalis and Other Organisms

Abstract

The virulence in mixed infections in mice with hemolysin producing or non-producing strain of Enterococcus faecalis and E. coli, K prieumoniae or P. aeruginosa was studied.
When mice were challenged intraperitoneary with the combination of a hemolysin producing strains of E. faecalis and other bacterial species, the virulence was more markedly enhanced than those of the combination of a non-hemolysin producing strain of E. faecalis and other bacterial species.
On the other hand, viable cells of E. coli in the blood of mice after mixed infectedwith a hemolysin non-producing E. faecalis and E. coli were remained longer than the case of the single infectionof E. coli.
Forethermore, it was confirmed that hemolysin producing E. faecalis was inhibited the bactericidal activity of mouse neutrophile.