Case of Varicella-zoster Pneumonia with Bronchioalveolar Lavage Confirmed by the Detection of VZV DNA in the Bronchial Washing by the Polymerase Chain Reaction

Abstract

A 32-year old male was admitted to our hospital conplaining of cough, fever, and skin eruptions. He was coctacted with a child who had chickenpox 3 weeks before the onset. He showed the elevating of antibody to varicella-zoster virus. Despite of the administration of Acyclovir for four days, cough was not relieved and a chest X-ray film showed infiltrative shadow in right middle lobe of the lung. Bronchoscopic examination revealed vasicle and edema, and the varicella-zoster virus (VZV) DNA was detected in the bronchoalveolar lavage by the polymerase chain reaction. The patient in first case confirmed by the virus DNA in the bronchial washing by thePCR.