Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
Case Reports
A case of early syphilitic hepatitis with hepatic granulomatous inflammation
Tomomitsu Matono, Shiho Tokunaga, Takaaki Sugihara, Takakazu Nagahara, Masaru Ueki, Kinya Okamoto, Kenji Ooyama, Keiko Hosho, Jyunichi Okano, Naoto Maeda, Masahiko Koda, Yoshikazu Murawaki, Yasushi Horie
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Keywords: early syphilitic hepatitis, laparoscopy, granulomatous inflammation
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2009 Volume 50 Issue 12 Pages 719-724

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Abstract

A 54-year-old man was admitted because of general fatigue and liver dysfunction. Positive results were obtained from serological testing for syphilis. An induration was identified on the penis, and small, white nodules were observed on the liver surface by laparoscopy. Pathological examination of the small nodules showed granulomatous inflammation. Spirochetes were not seen around the portal area in liver tissue. Early syphilitic hepatitis was diagnosed and amoxicillin administered for 4 weeks. Serum levels of transaminases and alkaline phosphatase rapidly normalized with treatment.

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© 2009 The Japan Society of Hepatology
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