Abstract
A 80-years-old woman was referred to our hospital for investigation of liver damage. Laboratory data and liver histology confirmed primary biliary cirrhosis (PBC). In this patient, a pancytopenia progressed gradually for a year, and the pericardium water retention suggesting pericarditis appeared in September, 2009. In addition antinuclear antibody was high tighter and double-stranded DNA antibody was positive. She was diagnosed as having systemic lupus erythematosus (SLE) according to diagnostic criteria of United States American College of Rheumatology and administration of the oral 20 mg prednisolone was started. At the same time, hepatocellular carcinoma (HCC), the diameter 22 mm in S2, left lobe of liver, was noted on abdominal enhanced computed tomography. In January, 2010, after confirming the improvement of pancytopenia and pericarditis, HCC was treated with both transcatheter arterial chemoembolization and radio frequency ablation. We reported the very rare case having PBC, SLE and HCC simultaneously.
