Primary inflammatory myofibroblastic tumor of the liver: case report

Abstract

Inflammatory myofibloblastic tumor (IMT) is defined as an intermediate biological potential tumor which rarely metastasizes. Histological finding of IMT is characterized by proliferation of spindle cells with intermingled variable inflammatory cells. While IMT originates in various organs, primary hepatic IMT is rare. Non-specific symptoms or image findings make its diagnosis difficult. Additionally, there are no established therapies. We described here a case of 31-year-old woman who underwent left hepatectomy for liver mass suspected malignant stromal cell tumor. Pathologic examination diagnosed this hepatic tumor as IMT. Local recurrence and metastatic lung tumor were recognized 7 months later, and both tumors were resected respectively. However, the patient died of liver failure by progression of local recurrence 12 months after the second surgery. Finally, we reviewed this rare tumor in the literature.