A case of primary hepatic neuroendocrine tumor which underwent a detailed image examine

Abstract

We reported a case of neuroendocrine tumor of the liver. A 57-years-old female was pointed out to have a liver tumor. At first, she was initially diagnosed as hemangioma of liver by CT and MRI. The serum was negative for hepatitis B surface antigen, core antigen, and for hepatitis C virus antibody. Tumor makers such as α-fetoprotein (AFP), protein induced by vitamin K absence or antagonist (PIVKA-II) were negative. The tumor size was enlarged by follow-up abdominal ultrasonography (US) findings after six months. US demonstrated irregular high echoic nodule. Plain CT showed a low density. In dynamic examination, the tumor showed marginal enhancement. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced MRI showed low intensity area on hepatobiliary phase. Single-level dynamic CTA showed ring enhancement. Esophagogastroduodenoscopy, colonoscopy and positron emission tomography (PET) CT did not reveal other malignancies. Tumor biopsy was performed for definitive diagnosis. The tumor was diagnosed pathologically as a neuroendocrine tumor. After diagnosis, partial hepatic resection was performed. She has been followed in the clinic without evidence of recurrence. Primary hepatic neuroendocrine tumor is rare, and so we report this case which appears to be of primary hepatic neuroendocrine tumor.