Fusobacteriumによる化膿性肝膿瘍9症例の臨床的検討―本邦報告例のreview―

重福 隆太; 渡邊 綱正; 得平 卓也; 中野 弘康; 服部 伸洋; 池田 裕喜; 松永 光太郎; 松本 伸行; 山本 博幸; 奥瀬 千晃; 鈴木 通博; 國島 広之; 伊東 文生

doi:10.2957/kanzo.59.23

Original Articles

Nine cases of pyogenic liver abscesses caused by Fusobacterium: Review and literature in Japan

Ryuta Shigefuku, Tsunamasa Watanabe, Takuya Ehira, Hiroyasu Nakano, Nobuhiro Hattori, Hiroki Ikeda, Kotaro Matsunaga, Nobuyuki Matsumoto, Hiroyuki Yamamoto, Chiaki Okuse, Michihiro Suzuki, Hiroyuki Kunishima, Fumio Itoh

Author information

Ryuta Shigefuku
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Tsunamasa Watanabe
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Takuya Ehira
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Hiroyasu Nakano
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Nobuhiro Hattori
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Hiroki Ikeda
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Kotaro Matsunaga
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Nobuyuki Matsumoto
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Hiroyuki Yamamoto
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
Chiaki Okuse
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kawasaki Municipal Tama Hospital
Michihiro Suzuki
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kawasaki Municipal Tama Hospital
Hiroyuki Kunishima
Division of Infectious Disease, St. Marianna University School of Medicine
Fumio Itoh
Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine

Keywords: pyogenic liver abscess, Fusobacterium necrophorum, Fusobacterium nucleatum, Lemièrre's syndrome, colorectal carcinoma

JOURNAL FREE ACCESS

2018 Volume 59 Issue 1 Pages 23-32

DOI https://doi.org/10.2957/kanzo.59.23

Details

Abstract

The aim of this study is to elucidate clinical features of pyogenic liver abscess (PLA) due to Fusobacterium (F-PLA). We report 9 F-PLA cases together with bibliographic consideration of previously reported in Japan. We diagnosed 9 F-PLA cased (7%) out of 125 PLA cases, from 1998 to 2017. Three cases were due to Fusobacterium species, 1 case was due to Fusobacterium necrophorum and 5 cases were due to Fusobacterium nucleatum. The median age was 76 year-old and male gender was predominated. Underlying diseases were intestinal disease, atrophic gastritis, pancreatic cancer, dental disease and pharyngitis. Notably, 6 cases of Fusobacterium nucleatum PLA with colorectal cancer were reported, and Fusobacterium necrophorum PLA patients are likely to be complicated by Lemièrre's syndrome, suggesting there might be different clinical features among different Fusobacterium species. All cases had good prognosis.

Corresponding author

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