A case of meningeal hemangiopericytoma with postoperative liver metastasis and hypoglycemia

Abstract

A 66-year-old man was admitted for the examination of the huge liver mass in the right lobe by abdominal ultrasonography. Five years earlier, he received an operation for meningeal hemangiopericytoma (HPC) at the department of neurosurgery in our hospital. In imaging studies, an approximately 15 cm mass of the right lobe and multiple metastases in the whole liver, multiple lung metastases, and multiple bone metastases including vertebral bodies were observed. The liver mass was pathologically diagnosed to be a metastatic HPC by an ultrasound-guided needle biopsy. Immunohistochemically, the tumor was positive for STAT6, high levels of Ki-67 positive, but are negative for synaptophysin, chromogranin A, hepatocyte, desmin, c-kit, S100, and CD34. He was re-hospitalized of hypoglycemic episodes 45 days after the first admission. After administering oral prednisolone, hypoglycemic episodes improved, and he died of tumor progression 124 days after admission.