妻の感染を契機に同居家族全員がA型肝炎ウイルスに感染した症例

斉藤 淳哉; 山島 美緒; 林田 稔也; 池田 智成; 石田 智士; 浦川 立貴; 岡村 卓真; 栗林 泰隆; 山道 忍; 矢嶌 弘之; 宮﨑 修; 本田 徹郎; 杉山 隆一; 清原 知子; 鈴木 亮介; 森内 浩幸; 市川 辰樹

doi:10.2957/kanzo.63.500

Short Communication

Household transmission of hepatitis A virus after infection of the mother

Junya Saito, Mio Yamashima, Toshiya Hayashida, Tomonari Ikeda, Satoshi Ishida, Tatsuki Urakawa, Takuma Okamura, Yasutaka Kuribayashi, Shinobu Yamamichi, Hiroyuki Yajima, Osamu Miyazaki, Tetsuro Honda, Ryuichi Sugiyama, Tomoko Kiyohara, Ryosuke Suzuki, Hiroyuki Moriuchi, Tatsuki Ichikawa

Author information

Junya Saito
Department of Gastroenterology, Nagasaki Harbor Medical Center
Mio Yamashima
Department of Gastroenterology, Nagasaki Harbor Medical Center
Toshiya Hayashida
Department of Pediatrics, Nagasaki University Hospital
Tomonari Ikeda
Department of Gastroenterology, Nagasaki Harbor Medical Center
Satoshi Ishida
Department of Gastroenterology, Nagasaki Harbor Medical Center
Tatsuki Urakawa
Department of Pediatrics, Nagasaki University Hospital
Takuma Okamura
Department of Gastroenterology, Nagasaki Harbor Medical Center
Yasutaka Kuribayashi
Department of Gastroenterology, Nagasaki Harbor Medical Center
Shinobu Yamamichi
Department of Gastroenterology, Nagasaki Harbor Medical Center
Hiroyuki Yajima
Department of Gastroenterology, Nagasaki Harbor Medical Center
Osamu Miyazaki
Department of Gastroenterology, Nagasaki Harbor Medical Center
Tetsuro Honda
Department of Gastroenterology, Nagasaki Harbor Medical Center
Ryuichi Sugiyama
Department of Virology II, National Institute of Infectious Diseases
Tomoko Kiyohara
Department of Virology II, National Institute of Infectious Diseases
Ryosuke Suzuki
Department of Virology II, National Institute of Infectious Diseases
Hiroyuki Moriuchi
Department of Pediatrics, Nagasaki University Hospital
Tatsuki Ichikawa
Department of Gastroenterology, Nagasaki Harbor Medical Center

Keywords: hepatitis A virus, familial transmission, genetic analysis

JOURNAL FREE ACCESS

2022 Volume 63 Issue 11 Pages 500-503

DOI https://doi.org/10.2957/kanzo.63.500

Details

Abstract

Hepatitis A virus (HAV) can spread among family members through fecal-oral transmission. We report a case of hepatitis A transmission within a family affecting the mother (index case), father, and their three daughters. The viral sequences obtained from the father and two daughters showed a nucleotide similarity ranging from 99.8% to 100%.

Prevention of the intrafamilial transmission of HAV infection requires strict adherence to contact precautions and immunization against HAV after diagnosis of the index case, which should have been considered for this family.

Corresponding author

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