2022 Volume 63 Issue 12 Pages 509-521
The updated version of JSH Guidelines for Management of Hepatitis B Virus (HBV) Infection (version 4) and JSH Guidelines for Management of Hepatitis C Virus (HCV) Infection (version 8.1) were published in June 2022 and May 2022, respectively. The JSH Guidelines for Management of HBV Infection (version 4) present recent evidences regarding management of HBV infections pre- and post-liver transplantation, management of chronic hepatitis B in childhood, NA for the prevention of mother-to-child transmission of HBV, and difference in the risk of hepatocellular carcinoma between TDF and ETV. This version also includes update of treatment goals, strategy for patients with good or poor responses to NA therapy, the IFN and NA combination therapy, HBV reactivation in immune checkpoint inhibitors, acute hepatitis B, HBV-related acute liver failure, and HBV and HIV co-infection. Meanwhile, the JSH Guidelines for Management of HCV Infection illustrates an updated flowchart of treatment for chronic hepatitis C and compensated cirrhosis type C.