Simultanous infection with type A and type B hepatitis viruses

Abstract

A man aged 26 with HBs·Ag positive liver cirrhosis suffered from acute type A hepatitis. There was sudden onset of fever, associated with increase in serum IgM concentration and appearance of atypical lymphocyte in peripheral blood in this patient. These symptoms are usually characteristic to acute type A hepatitis.
Infection on this patient with acute type A hepatitis was confirmed by serial detection of hepatitis A antibody.
It is interesting that titer of HBs·Ag in this patient transiently decreased by simultaneous infection of type A virus and returned to original level after recovery of type A hepatitis.