Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
A case of persistent elevation of serum glutamic oxaloacetic transaminase due to enzyme-immunoglobulin complex formation
Shinzo KATOHiromasa ISHIIToshikazu TAKAGIYoshiaki ASABAMakoto ICHIJOMasaharu TSUCHIYAShojiro KANOMieko SAGAKouji HORII
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1983 Volume 24 Issue 6 Pages 664-668

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Abstract

A 43 year-old male, who has no complaints, was admitted for the evaluation of the persistent elevation of serum Glutamic Oxaloacetic Transaminase (GOT) activity. He showed slight hepatomegaly, but no other abnormal findings in physical examination. The abnormal laboratory finding was found only in serum GOT level, and other tests including ECG, EMG, ICG-15 min, liver scintigram and histology of biopsied liver were normal.
By using electrophoresis and immuno-fixation technique, we found that serum GOT was bound to immunoglobulin Ig-G (λ) and forrned enzyme-immunogolbulin complex. Elevation of serum GOT seemed to be derived from the delayed disappearance rate of GOT from the blood, and not from the increase in release of GOT from the tissues.

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© The Japan Society of Hepatology
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