Abstract
The significance of the value of the molar ratio (Val+Ile+Leu/Phe+Tyr) is investigated in cases with portal hypertension.
The value of the molar ratio, which was correlated with the degree of hepatic encephalopathy by Fischer, is not so much correlated with the rate of slow waves in the EEG (θ+δ/α+θ+δ) as blood ammonia levels, and changed in few cases irrespective of the presence of hepatic encephalopathy.
Because a highly significant correlation existed between the value of the molar ratio and that of ICGR15, the value of the molar ratio was suggested to be useful to estimate the degree of liver damage.
Comparing the hepatofugal group with the hepatopetal group, the plasma branched amino acid concentrations had reciprocal relation with blood ammonia levels. So I supposed both had some mural relation on the matabolism of peripheral tissues.
