SOME PROBLEMS OF CHEMOTHERAPY IN TUBERCULOSIS IN VIEW OF THE RESULTS OF CULTURE OF RESECTED FOCI OF PULMONARY TUBERCULOSIS

Abstract

Cultivation of tubercle bacilli and drug resistance test were carried out on 500 resected specimens of pulmonary tuberculosis which were treated with chemotherapy before operation during the period from 1962 to 1966 in our sanatorium. The strains were defined as resistant if there was equal growth of tubercle bacilli on culture media containing 10 mcg SM, 1 mcg PAS, or 0.1 mcg INH. A schema useful for treatment was designed from the results of this study with special reference to the clinical course (Fig.5).