Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
ACTUAL CONDITION AND CHEMOTHERAPY FOR EXTRAPULMONARY TUBERCULOSIS IN NATIONAL SANATORIA (An Observation in Intestinal Tuberculosis and Tuberculous Peritonitis)
Report of The B Series of 26th Controlled Trials of Chemotherapy
Joichi KONISHIIKEMasazumi UNNOSatoru YAMAMOTO
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JOURNAL FREE ACCESS

1986 Volume 61 Issue 4 Pages 243-252

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Abstract

Out of 741 cases, admitted to the 39 institutions of national sanatoria, in which the clinical individual cards were available, 66 cases (8.9%) were intestinal tuberculosis and tuberculous peritonitis during the past five years (1978-1982).
Among 66 cases of both diseases, 48 cases with averaged 43.7 years, 32 males and 16 females, were intestinal tuberculosis and 18 cases with averaged 46.7 years, 3 males and 15 females, were tuberculous peritonitis.
Forty-five (93.8%) of the 48 intestinal tuberculous cases were associated with pulmonary tuberculosis, but in the 18 cases with tuberculous peritonitis, only 8 (44.4%) were associated cases.
The therapeutic effects of the regimens including RFP and INH for intestinal tuberculosis and tuberculous peritonitis were observed.
Response to these treatment is evaluated as effective except some aggravating cases, for intestinal tuberculosis without association of pulmonary tuberculosis and the optimum duration of chemotherapy is considered to be about twelve months.
In cases associated with pulmonary tuberculosis, however, the duration of chemotherapy should be prolonged to some extent, both in non-operated and operated cases, compared with cases without association.
Chemotherapy of tuberculous peritonitis was continued for 8.0 months in average in cases without association of pulmonary tuberculosis, and associated cases had responded well by continuing of 12.5 months in average.
In operated cases, either with or without association of pulmonary tuberculosis, results of their chemotherapy were shown to be well about in eleven to 15 months in average.
The mortality and morbidity from both diseases are appreciably less than in the prechemotherapy era. But the hospital mortality is still more 16.7 per cent (11 of the 66 cases) in this study.
Therefore, it is emphasized that early diagnosis and intensive chemotherapy at early stage of intestinal tuberculosis and tuberculous peritonitis are necessary andimportant for further improvement of clinical results and decreasing mortality.

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© THE JAPANESE SOCIETY FOR TUBERCULOSIS
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