Initiative in Electron Microscopic Support of ABiS

Abstract

Imaging techniques of electron microscopy are critical to observe ultrastructure in life science. Advanced technologies, such as cryo-electron microscopy and 3D ultrastructural analyses using scanning electron microscopy, have enabled visualization of 3D structures at high resolution and at various scales, from molecular complexes to cells and tissues. In addition, various techniques for visualizing specific molecules and structures within the ultrastructure have also become indispensable, serving as a bridge between other modalities of life science research and ultrastructural analyses. The electron microscopy support of ABiS provides a platform to meet the needs in utilizing such electron microscopic technologies. It allows experts to guide the direction of experiments, suggest appropriate analysis methods, and provide support with advanced skills for necessary electron microscopic experiments, based on the research objectives and the data already obtained. Additionally, through training of electron microscopy as well as the provision of advanced imaging techniques, the platform enhances the quality of research and the capabilities of researchers. These efforts will facilitate more research projects in wide areas of life science and be expected to make electron microscopy more accessible to a broader spectrum of researchers.