On the Infective Agents of Trachoma and Vaccinia

A special Study by Electron Microscopy

Abstract

1) The trachoma viruses, taken out purely from the human trachomatous tissues by differential ultracentrifugation, appeared on electron microscopic photographs as round granules about 130-170 millimicron in diameter.
2) The vaccinia viruses, taken out from the inoculated rabbit testes and troated similarly, appeared on the photographs likewise as round granules about 180-140 milli micron in diameter.
3) The viruses, of both the trachoma and vaccinia, were often accompanied with capsule-like attachments, which mainly consist of protein and are supposed to form a condition similar to protective colloid for the virus particles.