Time-Resolved Measurement of Light Pulse Transmittance through Strongly Scattering Media

Abstract

Near-infrared light is promising for measuring oxygenation of living bodies. Understanding of photon migration through living bodies is necessary, because light is strongly scattered by biological tissues. Among various simulation methods, a Monte Carlo method is regarded to be accurate because it can simulate all the paths of photon migration in strongly scattering media. Picosecond time-resolved transmittance measurement has been carried out to validate the Monte Carlo simulation results. However, differences have been observed between the measured and the Monte Carlo results where the reflection at the cell interfaces was neglected. In this research, a Monte Carlo simulation with consideration of reflection at the cell interfaces is carried out. The results are compared with the results of the time-resolved measurement, and good agreement is observed.