Effects of Shock Waves on Living Tissue Cell (Red Blood Cell) : Damage of Red Blood Cell and Mathematical Analysis of Deformation Model Using Spherical Shell Filled with Liquid

Abstract

This paper describes damage to living tissue cells induced by plane shock waves. It is an effective method for sensing injury to living tissue cells using pseudo-living cells. In this study, micro-capsules are used to estimate the degree of damage when subjected to shock waves. Mathematical models that can analyze displacement of living tissue cells and pressure in fluid when subjected to shock waves are evaluated. An elastic spherical shell is modeled to fit the biological data. Using stationary and transient analysis of spherical shell, the dynamic characteristics of the living cells (red blood cells and the micro-capsules) are obtained. The results show that damage to living tissue cells depends on (1) the elastic modulus of the cell, (2) the bulk modulus of intracellular material and (3) the thickness of cell membrane.