For cancer treatment, prompt and precise detection of the affected part is important in addition to urgent development of less-invasive approach to normal tissues. Herein, we investigated to utilize tumor-selective aggregation nature of a porphyrin derivative as an anchor structure of SPECT imaging protocol. Chelating sites for radioactive isotope elements were introduced into porphyrin periphery, which were not coordinated in a porphyrin core due to the large ion size.
