Co-host: The Chemical Society of Japan, The Society of Synthetic Organic Chemistry, Japan (Cooperation)
Alcohol molecules in water form self-association clusters through hydrogen-bonding interaction. This has been explained by the hydrophobic interaction. Therefore, the hydrogen-bonding network of water is thought to coexist with the alcohol clusters. However, by the mass spectrometric analysis of clusters in solutions, the new insights were provided as follows: (1) When the formation of alcohol clusters was promoted in water, hydrogen-bonded water clusters were not formed, (2) The alcohol self-association clusters were generated by the mixing with acetonitrile and dichloromethane as well as with water. The self-association of alcohol is found to be promoted by the mixing with the solvent which is difficult to solvate alkyl group of the alcohol.
