Abstract
We report a 5-year-old boy who presented excessive height velocity and penis enlargement, diagnosed with Leydig cell tumor. On initial presentation, height was 128.0 cm (+4.95 SD), weight was 26.7 kg (+3.6 SD), and bone age was 9 years 7 months. Tanner stage was G III P I, with a 6 ml testis on the right, 4 ml testis on the left, and 9 cm penis. Investigations revealed elevated testosterone (3.40 ng/ml), and suppressed gonadotropins (LH<0.10 IU/ml, FSH<0.20 IU/ml). From these results, we diagnosed gonadotropin-independent precocious puberty. The ultrasonography and MRI scan showed a mass in the right testis. High orchiectomy was performed, and the mass was diagnosed with Leydig cell tumor histologically. After surgery, height velocity slowed down and testosterone values decreased to the undetectable level.
