2019 Volume 69 Issue 1 Pages 37-41
Goodpasture's syndrome (GPS) is an autoimmune disease in which antibodies attack the glomerular basement membrane in lung and kidney, and is characterized by alveolar hemorrhage and rapidly progressive glomerulonephritis. Reccurence of this disease is rare due to the high success rate of remission induction and maintenance therapy. We report a 52-year-old man with GPS who had undergone steroid therapy and hemodialysis, and was in remission. Oral steroid use became increasingly difficult due to his nausea and vomitting. He was admitted to our hospital because alveolar hemorrhage recurred. Early intervention such as immunosuppressive therapy, plasma exchange therapy and careful management of his respiratory status enabaled his safe discharge. When immunosuppressive therapy is stopped shortly after induction of remission, GPS will occasionally relapse, and it is necessary to keep this possibility in mind.
