2025 Volume 75 Issue 3 Pages 291-293
A 34-year-old woman visited a nearby dental clinic with complaints of missing and loose teeth. Suspecting a bone dysplasia, she was referred to our department. She had been diagnosed with hypophosphatemic vitamin D-resistant rickets and received oral treatment until junior high school but discontinued follow-up visits on her own. Based on her symptoms and test results, she was re-diagnosed with X-linked hypophosphatemic rickets (XLH) , and we started to treat with burosumab (anti-FGF23 antibody) injections. Her occasional knee joint pain improved. In XLH, some patients discontinue treatment in childhood and revisit other departments in adulthood. For bone disorders such as XLH, it is important to educate patients from childhood about the need for continued treatment into adulthood and to raise awareness of such conditions among various medical departments.