A Case of Neurogenic Pulmonary Edema Following an Epileptic Seizure

Abstract

　　Neurogenic pulmonary edema (NPE) is a condition characterized by the development of pulmonary edema following acute central nervous system injury. Reports of NPE associated with epileptic seizures in children are extremely rare.

　　We report the case of a 14-year-old boy with a history of focal epilepsy who developed acute respiratory failure after two episodes of generalized convulsive seizures during sleep. Although the seizures were terminated with intravenous diazepam, severe hypoxemia persisted. Chest computed tomography demonstrated bilateral diffuse ground-glass opacities without evidence of intracranial pathology or cardiac disease. Laboratory findings showed no evidence of infection or metabolic abnormalities. Based on the clinical course and rapid improvement in oxygenation with supportive respiratory management, the patient was diagnosed with neurogenic pulmonary edema. His respiratory status improved within several days, and he was discharged without sequelae.

　　NPE should be considered in the differential diagnosis when acute respiratory failure persists after generalized seizures in pediatric patients.