Abstract
There are many reports on chemical prevention against and oxygen effect upon irradiation. However, no investigations seem to have yet been made on these effects in retina. The author performed irradiation upon guinea pig retina in vitro with concomitant application of cyanide, cysteine and glutathione, and under different gas conditions.
1. Anaerobic sugar metabolism in retina was inhibited by the irradiation, and the degree of the inhibition was Proportional with the dose of the irradiation.
2. Oxygen effect was recognized.
3. The elevation of sensitivity by NaCN, and protective effect of the concomitant application of cysteine and of glutathione were evidently observed in the air, in pure oxygen, and in pure nitrogen, respectively.
