Abstract
This report deals with an autopsy case of “INFECTIOUS MONONUCLEOSIS.” A 23-year old woman was admitted to the hospital, with complaints of slight fever, vomiting, abdominal pain and dyspnea. Soon after, high fever and cyanosis developed. After three days, she died of the respiratory disturbance. On section, there were marked enlargement of the general lymphoid tissues. Bronchitis and peribronchitis were remarkable. And hemorrhagic diathesis in wide spread organs such as lungs, bronchi, rectum, uterus, tonsils, heart and skin. Histologically, there was marked infiltration of atypical mononuclear cells in following organs- lymph nodes, tonsils, thymus gland, spleen, lungs, kidneys, liver, pharynx, stomach, small bowel, heart, salivary glands, adrenal glands, meninges and bone marrow. Their own structures were not destroyed by the mononuclear cell infiltration. In the liver, the mononuclear cells were seen in the Glisson's sheath, and liver cell necrosis was not recognized. The immediate cause of the death was the mononuclear cell infiltration to the lungs, followed by bronchitis and peribronchitis with hemorrage.