1976 Volume 26 Issue 2Supplement Pages 49-62
By in vitro and in vivo cellular immunologic test using a panel of antigens as SK-SD, PPD, and PHA, the delayed hypersensitivity in 6 patients with JRA and a patient with RA was found to be considerably impaired.
In an attempt to restore the immunosuppression in the JRA and RA, transfer facter was clinically applied to those patients with JRA and RA. There was a striking improvement in 6 out of 7 cases, concomitant with the development of cellular hypersensitivity to the antigens. But one patient with JRA showed neither any amelioration in general condition nor convertion of the skin reactivity. No untoward side effects of transfer facter have been apparently recognized.
These clinical results suggested that clinical application of transfer facter to JRA were more valuable to promise further study.
