Abstract
The relationship between plasma lysosomal enzyme levels and reticuloendothelial function was investigated in dogs subjected to hemorrhagic shock. 12 dogs were bled to a reservoir, maintaining mean arterial blood pressure 40 mmHg for two hours. They received shed blood after shock. Phagocytic indices were determined before and after shock using colloidal carbon as an indicator. Plasma β-glucuronidase levels were measured as a prototype of lysosomal enzymes according to Fishman's method before and after shock.
Phagocytic indices decreased significantly after shock and plasma β-glucuronidase elevated inversely after shock. A significant inverse correlation was observed between phagocytic index and plasma enzyme level.
