Abstract
1) The isolation frequency of clinical pathogen and their drug-resistances were surveyed by 9 public hospitals in Gunma Prefecture in Japan in 1986. 19682 strains were identified and 13780 strains were examined for 24 kinds of drug-resistances.
2) Among clinical isolates, 49% were Gram-negative rods and 42% were Gram-positive cocci. S. aureus (11.7%), E. coli (10.4%), P. aeruginosa (9.5%), and coagulase-negative staphylococci (9.5%) were the major bacterial species. Isolation frequency of these isolates were different in different clinical sources and in different hospitals.
3) Sixteen kind of species whose isolation frequency was more than 1 % were surveyed for their drug-resistances. There found a tendency of increase in drug-resistant bacteria in Serratia, Pseudomonas and S. aureus. Both the 3 rd-generation cephems and new quinolones were losing their antibacterial effect.
