1990 Volume 40 Issue 1 Pages 85-93
Heavy metals on human prostate were studied by sulfide-silver method and X-ray microanalysis. Samples were obtained from two normal prostates, fifteen hyperplastic prostates, two prostate cancers and one atrophic prostate which was castrated condition for 50 years period.
In the normal prostate, positive reactions were found in the prostatic epithelia and secretory products in the acini. Most nuclei did not show positive reaction, but some nuclei showed weakly positive. Hyperplastic prostate showed strongly positive reaction, especially in the apical part of cytoplasm and secretory products. Nuclei did not react positively. Silver granules could not find in the stroma. Moderately differentiated adenocarcinoma and castrated prostatic epithelial cells did not react positively by silver-sulfide method.
By X-ray microanalysis, reaction products by light microscopy were revealed the silver particles. Their locations were cytoplasm, especially in the apical part and secretory products in the lumen. Our results demonstrated the localization of the heavy metals on the prostatic tissues.
