STUDIES ON THE CELLULAR-IMMUNITY ACCORDING TO THE GRADE OF HISTOLOGICAL DEPTH OF INVASION IN GASTRIC CARCINOMA

MASAAKI TAKESHITA; TOORU WATANABE; TAMOTSU YAMADA; ISAO KOBAYASHI; SEIJI NAKAMURA; HITOSHI ISHIKAWA; MASARU IZUMI; YOSHIFUMI TANAHASHI; SUSUMU OWADA; YUKIO MIYAMOTO

doi:10.2974/kmj1951.41.199

MASAAKI TAKESHITA, TOORU WATANABE, TAMOTSU YAMADA, ISAO KOBAYASHI, SEIJI NAKAMURA, HITOSHI ISHIKAWA, MASARU IZUMI, YOSHIFUMI TANAHASHI, SUSUMU OWADA, YUKIO MIYAMOTO

Author information

MASAAKI TAKESHITA
Second Dept. of Surgery, Gunma University School of Medicine
TOORU WATANABE
Second Dept. of Surgery, Gunma University School of Medicine
TAMOTSU YAMADA
Second Dept. of Surgery, Gunma University School of Medicine
ISAO KOBAYASHI
Second Dept. of Surgery, Gunma University School of Medicine
SEIJI NAKAMURA
Second Dept. of Surgery, Gunma University School of Medicine
HITOSHI ISHIKAWA
Second Dept. of Surgery, Gunma University School of Medicine
MASARU IZUMI
Second Dept. of Surgery, Gunma University School of Medicine
YOSHIFUMI TANAHASHI
Second Dept. of Surgery, Gunma University School of Medicine
SUSUMU OWADA
Second Dept. of Surgery, Gunma University School of Medicine
YUKIO MIYAMOTO
Second Dept. of Surgery, Gunma University School of Medicine

Keywords: Invasion of gastric carcinoma, Skin test, Blastformation, Lymphocyte subsets, Metastasis to lymph node

JOURNAL FREE ACCESS

1991 Volume 41 Issue 1 Pages 199-207

DOI https://doi.org/10.2974/kmj1951.41.199

Details

Abstract

We investigated cellular immunity and the sate of metastasis to lymph nodes according to the depth of invasion in gastric carcinoma.
Skin tests (PHA, Su-PS, PPD), blastoformation (PHA, PWM) and T cell subsets (OKT 3, 4, 8, 4/8, Leu 11, 7) in peripheral blood and regional lymph nodes were evaluated.
In patients with carcinoma invading from the mucosa to the submucosa, skin tests, the number of T cell subsets, and blastformation were not depressed in peripheral blood and lymph nodes.
However cellular immunity was decreased and the rate of metastasis to lymph nodes was increased according to the invasion of carcinoma.

Corresponding author

Register with J-STAGE for free!