Abstract
A 43-year-old man with ulcerative colitis had severe irritative voiding symptoms manifested by frequency and pain on urination. The initial diagnosis was acute bacterial cystitis, and he received antimicrobial therapy. After initial treatment failure, a biopsy was performed and histological examination confirmed eosinophilic cystitis. The patient had been taking the herbal medicine “sairei-to” for 6 months. Dramatic resolution of his symptoms was obtained when discontinued taking the drug.