The KITAKANTO Medical Journal
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
STUDIES ON SERUM PROTEIN FRACTIONS IN SOME SURGICAL DISEASES
Hiroshi Yoneyama
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1959 Volume 9 Issue 2 Pages 280-303

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Abstract
1) Ether inhalation anesthesis and chemical hibernation in cases with hepatic disorder produced remarkable chauge in serum protein fractions.
2) In preerserved blood, with the prolongation of days of preservation, decrease in Al and increase in γ-Gl were shown.
3) Effect of blood transfusion on serum protein began to appear immediately after it, and around 20 hours, improvement in blood protein picture was observed. Thereafter it gradually returned to the pre-transfusion value. In the case of cancer, this improvement was not satisfactory despite sufficient amount of transfused blood, and the return to the pre-transfusion value was more rapid.
4) Dialysis with the artificial kidney on cases with renal insuffiency produced decrease in α2-Gl and increase in γ-Gl, which is closely related with hepatic disorder. Decrease in lipoprotein was due to blood transfusion and heparin, used as anticoagulant.
5) Change in serum protein picture in cancer was dependent on the site of its development, the state of its advance, hypotrophy, and hepatic function, and not on cancer itself.
6) Hepatic function and change in serum protein fractions after the operation showed close similarity, and had great bearing on determining serum protein picture.
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© The Kitakanto Medical Society
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