Abstract
We present a 52-year-old woman with Graves' disease, who was characterized by having both chronic thyrotoxic myopathy and posterolateral myelopathy. Both symptoms began and progressed concomitantly. After the administration of methimazole for treatment of Graves' disease, myopathy improved, while myelopathy remained unchanged. Various possible disorders to cause myelopathy were sought. However roentgenographic findings of entire spine X ray, myelogram, magnetic resonance imaging and cerebrospinal fluid examinations were all with negative results. The present data imply that rare manifestations associated with myelopathy in this patient may be due to thyrotoxicosis which is strongly linked to an abnormality in autoimmune mechanisms.
