A Cytological Study on the Pleomorphism of Oral Lactobacilli by Exposing to Several Chemical Agents

Abstract

From the references on the spontaneous occurrence of pleomorphic forms. in oral Lactobacilli, it was survayed that rod, coccoid, filamentous and crumpled forms were the major category of the classification of numerous dissociation in morphology. The morphological changes of L. acid. Harrison 3 A which grows normally rod was observed under the condition of the media containing sublethal dosis of common chemicals, Penicillinr Sublimate, Aureomycin, Acrinol, Homosulfamin, Urea and also under the pepton deficient media, and eventually it was approved to respond these given circumstances to rise filamentous, swollen, crumpled, coccoid forms. Judging from further cytological investigation, it was highly probable to consider that the resulted pleomorphism were by inhibition or disturbance of physiological process of cell function which was, in bacteriological cytology to be analysed to cell division, cell wall formation, divïsion of chromatinic body, cytoplasmic reproduction. In general, Lactobacilli belongs to rather sensitive genus against a little change in circumstance. Eventhough the media seemed to be normal for us, spontaneous pleomorphismm of oral strains on it, therefore, might be caused by unknown factors under which they were hard to maintain their healthy life, to be similltr to the harmful action of chemicals above.